Currently, we are working at the interface of chemistry, biology, and engineering to develop and apply novel nano-scale probes for biological measurements. In order to fulfill our goal of chemical imaging deep in the body (brain, central nervous system, circulatory system), we are approaching the problem through two directions. First, we are working with fluorescence-based sensors in cellular and tissue environments to understand the capabilities of the sensors for single-cell signaling. Second, we are tailoring our sensors to be compatible with advanced imaging techniques (photoacoustics, MRI) to image deep in the body. Ultimately, we will use the probes to image specific chemical processes in the body, in real-time.
The Clark Lab
Arizona State University
School of Biological and Health Systems Engineering
ASU Engineering Center, Tempe, AZ 85281